Long-term measles-induced immunomodulation increases overall childhood infectious disease mortality

Mina M, Metcalf C, de Swart R, Osterhaus A, Grenfell B.Science 2015;348:694-699. Palabra clave: Sarampión, Inmunomodulación, Mortalidad, Infancia Es conocido el efecto inmunosupresor del padecimiento del sarampión que predispone a padecer infecciones oportunistas durante periodos variables de tiempo, desde varias semanas a meses. La introducción de la vacuna en campañas masivas ha reducido la mortalidad…

Immunogenicity and reactogenicity of a decennial booster dose of a combined reduced-antigen-content diphtheria-tetanus-acellular pertussis and inactivated poliovirus booster vaccine in healthy adults

Kovak M, Rathi N, Kuriyakose Sh, Hardt K, Schwartz T.Vaccine 2015;33:2594-2601. Palabra clave: dTpa-VPI, Recuerdos, Inmunogenicidad, Reactogenicidad Estudio multicéntrico fase IV que evalúa la inmunogenicidad y reactogenicidad de una dosis de dTpa-VPI en adultos sanos que recibieron una dosis diez años antes de dTpa-VPI, de Td-VPI o dTpa+VPI. Vacunaron a 211 individuos con una edad…

MATS: global coverage estimates for 4CMenB, a novel multicomponent meningococcal B vaccine

Medini D, Stella M, Wassil J.Vaccine 2015;33:2629-2636. Palabra clave: Meningococo B, Vacunas, MATS Los autores, de GlaxoSmithKline, analizan los fundamentos de la técnica Meningococcal Antigen Typing System (MATS) como subrogado de la actividad bactericida sérica (ABS) para conocer la cobertura potencial de la vacuna multicomponente frente a meningococo B en varios países europeos. La técnica…

Direct benefit of vaccinating boys along with girls against oncogenic human papillomavirus: Bayesian evidence synthesis

Bogaards J, Wallinga J, Brakenhoff R, Meijer Ch, Berkhof J.Br Med J 2015;350:h2016. Palabra clave: Papilomavirus humano, Vacuna, Varones Mediante un modelo bayesiano, los autores evalúan la reducción de la carga de cáncer prevenible en varones si se vacunan los chicos, además de las chicas, frente a los tipos oncogénicos de papilomavirus. El modelo lo…

Actualización del Pink Book 2015, con webinars, seminarios etc Pink Book 2015

The latest edition of the Pink Book, published in May 2015, replaces the previous version which was released in 2012. The 13th Edition Epidemiology and Prevention of Vaccine-Preventable Diseases, a.k.a. the “Pink Book,” provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on routinely used vaccines and the diseases…

Actualización del Pink Book 2015, con webinars, seminarios etc Pink Book 2015

The latest edition of the Pink Book, published in May 2015, replaces the previous version which was released in 2012. The 13th Edition Epidemiology and Prevention of Vaccine-Preventable Diseases, a.k.a. the “Pink Book,” provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on routinely used vaccines and the diseases…

Actualización del Pink Book 2015, con webinars, seminarios etc Pink Book 2015

The latest edition of the Pink Book, published in May 2015, replaces the previous version which was released in 2012. The 13th Edition Epidemiology and Prevention of Vaccine-Preventable Diseases, a.k.a. the “Pink Book,” provides physicians, nurses, nurse practitioners, physician assistants, pharmacists, and others with the most comprehensive information on routinely used vaccines and the diseases…